Basic Radiobiology

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Link to IAEA Radiation Oncology Physics: A Handbook for Teachers and Students
Slides: Chapter 14. BASIC RADIOBIOLOGY
Text: Chapter 14. BASIC RADIOBIOLOGY

Contents 1 Introduction 2 Classification of Radiations in Radiobiology 3 Cell Cycle and Cell Death 4 Irradiation of Cells 5 Type of Radiation Damage 6 Cell Survival Curves 7 Dose Response Curves 8 Measurement of Radiation Damage in Tissue 9 Normal and Tumour Cells: Therapeutic Ratio 10 Oxygen effect 11 Relative Biological Effectiveness 12 Dose Rate and Fractionation 13 Radioprotectors and Radiosensitizers 14 BIBLIOGRAPHY

[edit] Introduction

[edit] Classification of Radiations in Radiobiology

[edit] Cell Cycle and Cell Death

[edit] Irradiation of Cells

1. Direct action in cell damage by radiation
2. Indirect action in cell damage by radiation
3. Fate of irradiated cells

[edit] Type of Radiation Damage

1. Timescale
2. Classification of radiation damage
3. Somatic and genetic effects
4. Stochastic and deterministic (non-stohastic) effect
5. Acute versus late tissue or organ effects
6. Total body radiation exposure
7. Foetal irradiation

[edit] Cell Survival Curves

[edit] Dose Response Curves

[edit] Measurement of Radiation Damage in Tissue

[edit] Normal and Tumour Cells: Therapeutic Ratio

[edit] Oxygen effect

[edit] Relative Biological Effectiveness

[edit] Dose Rate and Fractionation

[edit] Radioprotectors and Radiosensitizers

[edit] BIBLIOGRAPHY